👉 The Blair Fluid, also known as Blair's Transfusion Reaction, is a rare and potentially life-threatening condition that occurs when blood transfusions are performed using blood components from donors with a specific antigen called Kell (K). This antigen is present in red blood cells, and when Kell-positive blood is transfused into Kell-negative recipients, it can trigger an immune response. The body recognizes the Kell antigen as foreign and produces antibodies against it, leading to a severe immune reaction that can cause fever, chills, back pain, and in extreme cases, organ failure or even death. To prevent this, strict screening protocols are implemented to ensure that blood components are matched carefully and Kell-negative blood is reserved for patients requiring transfusions.
